Some of the most common toxic effects of MAOIs include:
Hypertensive Crisis: This is a rapid and dangerous increase in blood pressure that can occur if MAOIs are taken with foods rich in tyramine or certain medications. Serotonin Syndrome: This condition can result from excessive serotonergic activity in the brain, often due to the combination of MAOIs with other serotonergic drugs. Central Nervous System Effects: These can include agitation, confusion, and seizures. Orthostatic Hypotension: A drop in blood pressure upon standing, which can lead to dizziness and falls. Hepatotoxicity: Liver damage is a less common but serious side effect associated with some MAOIs.