N-Acetyltransferases (NATs) are a family of enzymes that play a crucial role in the metabolism of various drugs and endogenous compounds. These enzymes catalyze the transfer of an acetyl group from acetyl-CoA to a substrate, which can be a drug, a xenobiotic, or an endogenous compound such as serotonin. NATs are encoded by the NAT1 and NAT2 genes in humans.
