NMDA receptor antagonists are compounds that inhibit the action of N-Methyl-D-aspartate (NMDA) receptors in the brain. These receptors are a subtype of glutamate receptor and play a vital role in synaptic plasticity, memory function, and excitatory neurotransmission. By blocking these receptors, NMDA antagonists can alter brain function significantly, leading to both therapeutic and adverse effects.
