genetic variations

What are Some Examples of Genetic Variations Impacting Toxicology?

Several genetic variations have been identified that impact toxicology:
GSTM1: Deletion of this gene can impair detoxification of carcinogens, increasing cancer risk.
NAT2: Variations can lead to slow or fast acetylation, affecting the metabolism of certain drugs and carcinogens.
ALDH2: Variations can impact alcohol metabolism, influencing the risk of alcohol-related disorders.

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