Numerous compounds are known to inhibit transporters. For instance, Cyclosporine is a well-known inhibitor of P-glycoprotein and can affect the distribution and excretion of co-administered drugs. Similarly, Rifampicin is an inhibitor of OATP transporters, which can alter the pharmacokinetics of other drugs and toxicants. These inhibitors are crucial in understanding drug-drug interactions and predicting toxicological outcomes.
