For patients who experience severe side effects or hypersensitivity reactions, alternatives to Taxol such as docetaxel or nab-paclitaxel may be considered. Nab-paclitaxel, for instance, is a formulation of paclitaxel bound to albumin, which does not require Cremophor EL and is associated with a reduced risk of hypersensitivity reactions. However, the choice of alternative therapy depends on the specific cancer type and the patient's overall health profile.