What are the Applications of Transcriptomics in Toxicology?
Mechanistic Understanding: Transcriptomics helps in understanding the mechanisms by which toxicants exert their effects, revealing pathways and networks that are disrupted. Biomarker Discovery: Identifying specific gene expression changes as biomarkers aids in the early detection of toxic effects and in monitoring exposure levels. Risk Assessment: By comparing transcriptomic profiles, researchers can better assess the risk posed by different chemicals and prioritize them for regulatory action. Drug Development: Understanding toxicological pathways can inform the development of safer drugs by predicting potential adverse effects early in the drug discovery process.
