What are the Challenges in Biocatalysis for Toxicology?
Despite its benefits, biocatalysis in toxicology faces several challenges. The variability of enzyme activity among individuals, due to genetic differences, can lead to unpredictable responses to toxins and drugs. Additionally, some enzymatic reactions can produce more harmful intermediates than the original substances. Researchers are continuously exploring ways to manipulate and enhance enzymatic pathways to improve safety and efficacy in detoxification and drug development.