What Are the Challenges in Studying Chemical Carcinogenesis?
Studying chemical carcinogenesis presents several challenges. Firstly, the long latency period between exposure and cancer development makes it difficult to establish direct causation. Additionally, humans are often exposed to mixtures of chemicals rather than single agents, complicating the assessment of individual chemical contributions. Ethical considerations also limit the extent of experimental studies involving human subjects, necessitating reliance on animal models and computational methods.