Respect for Persons: This principle emphasizes the autonomy of individuals and the necessity to obtain informed consent. In toxicology, this means ensuring that participants are fully aware of the potential risks and benefits of a study involving exposure to chemicals or toxins. Beneficence: Researchers are obligated to minimize harm and maximize benefits. In toxicological research, this could involve rigorous safety assessments, dose-response studies, and ethical review processes to ensure participant safety. Justice: This principle requires equitable distribution of the risks and benefits of research. In toxicology, it urges researchers to avoid exploiting vulnerable populations or conducting studies that disproportionately affect certain groups.