What Are the Defense Mechanisms Against Oxidative Damage?
Cells possess several defense mechanisms to counteract oxidative damage. Antioxidant enzymes like superoxide dismutase (SOD), catalase, and glutathione peroxidase play crucial roles in detoxifying ROS. Non-enzymatic antioxidants such as vitamin C, vitamin E, and glutathione also help neutralize free radicals. The body maintains a delicate balance between ROS production and antioxidant defenses to prevent oxidative stress.
