Various toxicants can have detrimental effects on T cells, leading to impaired immune responses. Some known effects include:
- Immunosuppression: Reduced T cell proliferation and cytokine production. For example, exposure to cytostatic drugs can inhibit T cell function, making the body more susceptible to infections. - Autoimmunity: Certain chemicals can trigger an autoimmune response by altering T cell function, leading to conditions like lupus or multiple sclerosis. - Allergies: Chemicals in cosmetics or industrial products can sensitize T cells, causing allergic reactions upon subsequent exposures.