What Are the Key Components of Preclinical Testing?
Preclinical testing typically involves in vitro and in vivo studies. In vitro studies are conducted using cell cultures to assess the drug's cytotoxicity and biological activity. In vivo studies involve testing in animal models to evaluate the drug's safety profile, including acute toxicity, chronic toxicity, carcinogenicity, and teratogenicity. These studies help in understanding the drug's ADME (Absorption, Distribution, Metabolism, and Excretion) properties.
