What are the Recent Advances in HepG2 Cell Research?
Recent advances in HepG2 cell research include the development of 3D culture systems and organ-on-a-chip technologies that aim to better replicate the liver's complex environment. These innovations improve the predictive accuracy of in vitro models for human liver toxicity. Additionally, CRISPR-Cas9 gene editing is being used to modify HepG2 cells to express higher levels of specific drug-metabolizing enzymes, enhancing their utility in toxicological studies.