What are the Therapeutic Approaches for LPS-Induced Toxicity?
Treatment of LPS-induced toxicity involves targeting the inflammatory response. Anti-inflammatory drugs such as corticosteroids are often used to mitigate the effects. Additionally, monoclonal antibodies targeting specific cytokines like TNF-α are under investigation. The use of antibiotics to eliminate Gram-negative bacteria is another approach but must be managed carefully to avoid endotoxin release upon bacterial lysis.