What are the Therapeutic Uses of Tubulin Inhibitors?
Tubulin inhibitors are valuable in the treatment of cancers due to their ability to halt cell division. Drugs such as vinca alkaloids (e.g., vincristine and vinblastine) and taxanes (e.g., paclitaxel) are used in chemotherapy to exploit the rapid division of cancer cells. By stabilizing or destabilizing microtubules, these drugs prevent the successful completion of mitosis, leading to cell death.