What are the toxicological concerns associated with Anthracyclines?
While effective, anthracyclines are associated with significant toxicological concerns. The most notable is cardiotoxicity, which can lead to irreversible heart damage and heart failure. The risk increases with cumulative dosing, making it a crucial consideration in therapy planning. Myelosuppression, gastrointestinal disturbances, and alopecia are other common toxicities.
