What are the Toxicological Implications of Xanthine Oxidase Inhibition?
Inhibiting xanthine oxidase can be beneficial in conditions where excessive uric acid production and ROS generation are detrimental. Allopurinol and febuxostat are well-known xanthine oxidase inhibitors used in the treatment of gout, a disease characterized by the accumulation of uric acid crystals in the joints. By reducing uric acid levels and ROS production, these inhibitors help alleviate inflammation and oxidative stress, providing therapeutic benefits.
