Treatment for drug overdose depends on the substance involved. In cases of opioid overdose, naloxone is a life-saving medication that can rapidly reverse the effects of opioids. For other drugs, supportive care, such as maintaining airway patency and providing intravenous fluids, may be necessary. Activated charcoal can be administered in some cases to limit drug absorption in the gastrointestinal tract. Prompt medical attention is crucial in managing overdoses effectively.