Treatment of lipodystrophy focuses on managing metabolic complications and addressing cosmetic concerns. Lifestyle modifications, including diet and exercise, can help improve insulin sensitivity and lipid profiles. In some cases, switching medications may be necessary. For instance, patients on antiretroviral therapy might be switched to alternative regimens with a lower risk of lipodystrophy. In severe cases, surgical interventions such as fat grafting or liposuction may be considered to address specific areas of fat loss or accumulation.
