Cutaneous reactions can be triggered by a variety of substances, including chemicals, drugs, and environmental toxins. Common causes include:
- Chemical Irritants: Substances such as acids, alkalis, and solvents can cause direct damage to the skin, leading to irritant contact dermatitis. - Allergens: Certain chemicals and drugs can act as allergens, provoking an immune response that results in allergic contact dermatitis. - Photosensitizers: Some substances can cause reactions when the skin is exposed to sunlight, known as photosensitivity reactions. - Systemic Toxicants: Toxins ingested or absorbed into the body can manifest as skin reactions, indicating a systemic issue.