Several factors can lead to elevated homocysteine levels:
Genetic Factors: Mutations in genes such as MTHFR (methylenetetrahydrofolate reductase) can impair the metabolism of homocysteine. Nutritional Deficiencies: Insufficient intake of vitamins B6, B12, and folate can disrupt homocysteine metabolism. Lifestyle Factors: Smoking, excessive alcohol consumption, and a sedentary lifestyle can contribute to higher levels. Medical Conditions: Conditions such as renal disease and hypothyroidism can also lead to elevated homocysteine.
