Elevated homocysteine, a condition known as hyperhomocysteinemia, is linked to an increased risk of cardiovascular diseases, including coronary artery disease and stroke. It is believed that high levels of homocysteine can damage the endothelial lining of blood vessels, leading to atherosclerosis. Additionally, hyperhomocysteinemia has been implicated in neurodegenerative diseases like Alzheimer's and in complications during pregnancy.