Photodermatitis can be triggered by a variety of factors, including the ingestion or topical application of photosensitizing agents. These agents include certain medications such as tetracyclines, sulfonamides, and nonsteroidal anti-inflammatory drugs (NSAIDs), as well as some plant-based compounds like furocoumarins found in citrus fruits. In addition, certain perfumes and skincare products that contain photosensitizing ingredients can also contribute to the condition.