individual susceptibility

What Factors Contribute to Individual Susceptibility?

Several factors can influence an individual's susceptibility to toxins:
Genetic Makeup: Genetic variations can affect how a person metabolizes or responds to toxins. For instance, polymorphisms in genes encoding for enzymes such as cytochrome P450 can result in differences in the metabolism of drugs and chemicals.
Age: Age can significantly affect susceptibility. Children and the elderly often have different metabolic rates and organ functions compared to adults, making them more or less susceptible to certain toxins.
Sex: Hormonal differences between males and females can lead to variations in susceptibility. For example, estrogen can influence the metabolism of some drugs and chemicals.
Health Status: Pre-existing conditions such as liver or kidney disease can impair the body's ability to detoxify substances, increasing susceptibility.
Lifestyle: Factors like diet, alcohol consumption, and smoking can influence how toxins are processed in the body.

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