What Innovations Are Enhancing TEM Application in Toxicology?
Recent advances in TEM technology, such as cryo-TEM, have expanded its applications in toxicology by enabling the examination of biological samples in a more native state. Cryo-TEM involves rapidly freezing samples to preserve their structure without chemical fixation, reducing artifacts and allowing for more accurate analyses of toxic effects. Additionally, developments in automated image analysis and 3D reconstruction are enhancing the capability of TEM to provide detailed insights into the mechanisms of toxicity.