Neuroleptic Malignant Syndrome (NMS) is a rare but potentially fatal condition associated with haloperidol and other antipsychotics. It is characterized by a triad of symptoms: hyperthermia, muscular rigidity, and autonomic dysfunction (such as tachycardia and unstable blood pressure). Early recognition and immediate discontinuation of the drug are crucial, followed by supportive care and, in some cases, the administration of medications such as dantrolene or bromocriptine.