Structural biology is a branch of molecular biology concerned with the study of the architecture and shape of biological macromolecules. It employs techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and cryo-electron microscopy to determine the 3D structures of proteins, nucleic acids, and other complex assemblies. Understanding these structures is essential for elucidating the function of biomolecules and their interactions with other molecules, including potential toxicants.