The Aryl Hydrocarbon Receptor (AhR) is a ligand-activated transcription factor that is part of the basic helix-loop-helix Per-ARNT-Sim (bHLH-PAS) family. It plays a crucial role in mediating the effects of environmental toxins such as dioxins and polycyclic aromatic hydrocarbons (PAHs). AhR is found in various tissues and is involved in the regulation of genes associated with xenobiotic metabolism, immune response, and cell cycle control.
