What is the Impact of Blood-Brain Barrier on Toxin Distribution?
The blood-brain barrier (BBB) is a selective permeability barrier that protects the central nervous system from potentially harmful substances in the bloodstream. It poses a significant challenge in toxicology as it restricts the entry of many toxins, but some, such as alcohol and certain drugs, can cross the BBB and cause neurological effects. Understanding the BBB is crucial for assessing the neurotoxic potential of substances.
