atp binding cassette transporters

What is the Role of Genetic Variability in ABC Transporters' Function?

Genetic polymorphisms in ABC transporter genes can significantly impact their expression and function, influencing individual responses to drugs and susceptibility to toxins. These genetic variations can alter the pharmacokinetics of therapeutic agents and are a focus of pharmacogenomic studies aimed at personalizing medicine to improve safety and efficacy.

Frequently asked queries:

What are ATP Binding Cassette Transporters?
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What are the Main Types of ABC Transporters Involved in Toxicology?
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Can ABC Transporters Be Targeted to Overcome Drug Resistance?
What is the Role of Genetic Variability in ABC Transporters' Function?
How Do Environmental Factors Influence ABC Transporters?
How Does Km Affect the Design of Antidotes?
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