genetic and epigenetic

What is the Role of Genetics in Toxicology?

Genetics plays a crucial role in toxicology by influencing individual susceptibility to toxins. Genetic variations, such as single nucleotide polymorphisms (SNPs), can affect how a person metabolizes and responds to toxic substances. For instance, variations in genes encoding for cytochrome P450 enzymes can alter the rate at which toxins are metabolized, impacting their toxicity levels. This genetic diversity is a key factor in understanding why some individuals are more vulnerable to the harmful effects of certain chemicals than others.

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