Individual susceptibility to toxicants can vary greatly due to genetic, physiological, and environmental factors. Important considerations include:
- Genetic Variability: Polymorphisms in genes encoding for metabolic enzymes can influence how an individual processes toxic substances. - Age and Health Status: Vulnerable populations such as infants, the elderly, and individuals with pre-existing conditions may be more susceptible to toxic effects. - Lifestyle Factors: Diet, alcohol consumption, and smoking can alter the metabolism and toxicity of chemicals.