What is the Role of Nuclear Receptors in Endocrine Disruption?
Endocrine disruptors are chemicals that can interfere with hormonal systems, and nuclear receptors are often the targets of these interactions. For example, the Estrogen Receptor (ER) and the Thyroid Hormone Receptor (TR) can be activated or inhibited by various environmental chemicals, leading to disrupted hormonal signaling. This can result in developmental, reproductive, and metabolic abnormalities.
