What Is the Role of Peptidases in Drug Metabolism?
Peptidases are integral to the metabolism of peptide-based drugs and pro-drugs. They can influence the pharmacokinetics and pharmacodynamics of these substances by altering their bioavailability and activity. Understanding how peptidases interact with drugs is crucial for predicting drug behavior and potential toxic effects. This knowledge can guide the design of drugs with improved safety profiles by minimizing adverse interactions.