Vitamin D toxicity, or hypervitaminosis D, occurs when there is an excessive accumulation of vitamin D in the body, typically due to over-supplementation. This condition can lead to hypercalcemia, where calcium levels in the blood become excessively high, potentially resulting in nausea, vomiting, weakness, and serious complications such as kidney damage. Itâs important to monitor vitamin D levels, especially if you are taking supplements, to avoid these adverse effects.