Several methods are employed in signal detection, including:
Data Mining: Utilizing large databases to identify patterns and associations that suggest potential toxicity. Pharmacovigilance: Monitoring the effects of drugs after they have been released to the market to identify previously unreported adverse effects. Epidemiological Studies: Observational studies that track health outcomes in specific populations exposed to potential toxins. In Silico Modeling: Using computer simulations to predict toxicological effects based on chemical structure and biological pathways. In Vitro Testing: Laboratory-based experiments on cell cultures to assess the toxicity of substances.
