Which Substances Are Commonly Associated with Lactic Acidosis?
Several substances are implicated in causing lactic acidosis, including:
Metformin: Especially in cases of overdose or renal impairment. Cyanide and carbon monoxide: Both disrupt oxidative phosphorylation. Salicylates: High doses can lead to increased lactate production. Propylene glycol: Found in medications and can accumulate in the body. Ethanol and methanol: Their metabolites can lead to increased lactate levels.
