Traditional nanomaterials, such as metal-based nanoparticles, can accumulate in the body and the environment, posing long-term health risks. Biodegradable nanomaterials, on the other hand, degrade into biocompatible or easily excretable byproducts, minimizing chronic toxicity and environmental contamination. This makes them a safer alternative for various applications, particularly in medical treatments where prolonged exposure to non-degradable materials could lead to adverse effects.