Why is Acetaldehyde Dehydrogenase Important in Toxicology?
In the field of toxicology, understanding the role of ALDH is crucial because acetaldehyde is a highly reactive and toxic compound. It can cause DNA damage, protein adduct formation, and lipid peroxidation. Prolonged exposure to acetaldehyde, often due to excessive alcohol consumption or genetic variations affecting ALDH function, can lead to serious health issues, including liver disease and an increased risk of cancer.
