The AR assay is crucial in toxicology for several reasons. First, it helps in identifying chemicals that may disrupt the endocrine system, which can lead to reproductive, developmental, and metabolic disorders. Second, it aids in the assessment of the carcinogenic potential of compounds, as androgen receptors are implicated in certain cancers, such as prostate cancer. Lastly, AR assays are part of regulatory requirements for chemical safety evaluations, helping to ensure that compounds released into the environment or used in consumer products are safe.
