Excretion is the process of eliminating a substance from the body, primarily through urine, feces, and to a lesser extent, through sweat and expired air. The rate and route of excretion influence the duration and intensity of exposure to the toxicant. Impaired excretion, due to renal or hepatic dysfunction, can lead to accumulation of the toxicant and increased risk of toxicity. Evaluating excretion mechanisms is crucial for developing detoxification strategies and assessing the potential for chronic exposure.
