Are there any therapeutic interventions targeting NPC1 and NPC2 dysfunction?
Therapeutic interventions for NPC1 and NPC2 dysfunction focus on restoring lipid homeostasis. For instance, cyclodextrin has been studied as a potential treatment that aids in cholesterol mobilization from lysosomes. In the context of toxicology, these therapies may mitigate the toxic effects of lipid accumulation due to genetic or environmental factors.
