How do NPC1 and NPC2 relate to toxicological processes?
In toxicology, the function of NPC1 and NPC2 genes is significant due to their involvement in the cellular handling of cholesterol and other lipids. Disturbances in lipid homeostasis can have toxic effects, leading to cellular stress and damage. For example, impaired function of these genes can lead to an accumulation of toxic substances within cells, contributing to neurodegeneration and liver disease.
