How do environmental toxins interact with NPC1 and NPC2 genes?
Exposure to certain environmental toxins can affect the expression and functionality of the NPC1 and NPC2 genes. For instance, some xenobiotics may disrupt lipid metabolism, increasing the burden on these genes to maintain lipid homeostasis. Moreover, toxins that affect lysosomal function can hinder the activity of NPC1 and NPC2, potentially leading to toxic accumulation of lipids.
