Given its central role in drug metabolism and detoxification, PXR is a potential target for therapeutic intervention. Modulating PXR activity could optimize drug therapy by minimizing adverse reactions and enhancing drug efficacy. Some research is focused on developing PXR antagonists to prevent unwanted drug interactions. Furthermore, understanding PXR's role in metabolic diseases could pave the way for novel treatments in conditions like non-alcoholic fatty liver disease (NAFLD).
