Toxicological evaluations within the Codex framework are conducted by expert panels such as JECFA and JMPR. These evaluations involve reviewing scientific data on the toxicology of substances, including studies on their acute toxicity, chronic toxicity, carcinogenicity, and other health effects. The panels also assess potential exposure levels through food consumption and determine safe exposure limits. These evaluations are crucial for establishing ADIs and MRLs that ensure food safety.
