Managing taxane toxicity involves a combination of dose adjustments, supportive care, and premedication. Dose reductions or delays may be necessary for patients experiencing severe side effects. Supportive care includes the use of growth factors to manage myelosuppression and analgesics or antidepressants to alleviate neuropathic pain. Premedication with corticosteroids and antihistamines can mitigate hypersensitivity reactions.