How Can Tyrosine Kinase Inhibitors Be Used in Toxicology?
Tyrosine kinase inhibitors (TKIs) are a class of drugs designed to block the action of tyrosine kinases. These inhibitors are crucial in cancer therapy, as they can specifically target and inhibit the aberrant kinases driving tumor growth. In toxicology, the study of TKIs helps in evaluating their safety, efficacy, and potential side effects. Moreover, TKIs can serve as a model for understanding how other compounds might interact with kinase pathways, providing insights into their toxicological profiles.