In the context of toxicology, tyrosine kinases are significant because they are involved in the pathways that can lead to cancer and other diseases. When these enzymes become dysregulated, either through overexpression, mutation, or other mechanisms, they can contribute to the uncontrolled proliferation of cells, a hallmark of cancer. Thus, understanding their role can aid in the development of therapeutic interventions and in assessing the risks posed by various chemical exposures.
